02 Feb '11, 2am

Cancer drug, when combined, boosts death risk

WASHINGTON: The cancer drug Avastin, also known as bevacizumab, is linked to a higher risk of death when combined with chemotherapy, said a study Tuesday in the Journal of the American Medical Association. The drug has previously been found to raise the risk of blood clots in the legs and lungs by 33 percent, and in December the US Food and Drug Administration said it was neither safe nor effective against breast cancer. Bevacizumab, marketed as Avastin by the Swiss drug giant Roche, has been approved for use in combination with chemotherapy for treating colorectal cancer, non-small cell lung cancer and renal cell carcinoma. The growth of new blood vessels helps spread cancer and Avastin is designed to fight the disease by inhibiting the proliferation of new blood vessels. The JAMA study led by Vishal Ranpura and doctors at Stony Brook University Medical Center in New York...

Full article: http://www.channelnewsasia.com/stories/health/view/110841...

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todayonline.com 02 Feb '11, 5am

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